Platelet Rich Plasma (PRP) is blood plasma that has been enriched with platelet. As a concentrated source of autologous platelets, PRP contains (and releases through degranulation) several different growth factors and other cytokines that stimulate healing of the bone and soft tissue.
To create PRP, a small sample of your blood is drawn (similar to a lab test sample) and placed in a centrifuge that spins the blood at high speeds, separating the platelets from the other components.
The PRP is then injected into and around the point of injury, jump-starting and significantly strengthening the healing process.
Because your own blood is used, there is no risk of a transmissible infection and a low risk of allergic reaction.
blood-derived growth factors.
The internal essence of your blood contains life-giving fundamental protein growth factors. PRP utilizes a leading-edge patented technology specifically designed. With a simple quick and advantageous process, Dr Grossman is able to derive a high concentration of biological nutrient-rich cells and create autologous platelet-rich plasma.
- Dr Grossman draws a similar amount of blood required for a basic lab test.
- He then places the blood into a centrifuge and spins the blood at a very rapid rate to separate the platelets from the other components of the blood.
- The platelet-rich plasma is activated to release at least 8 essential growth factors and signaling proteins. Platelet-rich plasma is a technology that deploys aspects of the blood based biochemistry. Because all constitutes retrieved in PRP are exclusively from the patient (autologous in origin), there is virtually no risk of an allergic reaction or intolerance. Nevertheless, before any treatment disclose all the medications you are taking (including herbs) with Dr Grossman.
GROWTH FACTOR PRODUCTION KNOWN EFFECTS.
Epidermal Growth Factor (EGF)
Plays a significant role in the regulation of cell growth, proliferation, and the differentiation during the remodeling phase. Stimulates keratinocyte and fibroblast production.
Transforming Growth Factor (TGF)
Promotes angiogenesis which is the physiological process involving the growth of new blood vessels.
Vascular Endothelial Growth Factor (VEGF)
An important signaling protein involved in both vasculogenesis and angiogenesis, the growth of the blood vessels from pre-existing vasculature.
Fibroblast Growth Factor (FGF)
Promotes angiogenesis, granulation, and epithelialization for the intricate process of the skin repairing itself after injury.
Platelet-Derived Growth Factor (PDGF)
Attracts macrophages and fibroblasts to the zone of injury. Promotes collagen growth and proteoglycan synthesis.
Interleukins, Macrophages, keratinocytes, endothelial cells, Iymphocytes, fibroblasts, osteoblasts, basophils, mast cells.
Activates fibroblasts differentiation. Induces collagen and proteoglycan synthesis for healthy cell production and repair of damaged tissues.
Collagen Stimulating Growth Factor.
Stimulates granulocyte and macrophage proliferation for the growth of healthy tissue and blood cells.
Keratinocyte Growth Factor (KGF)
Keratinocyte migration, differentiation, and proliferations directly enhance wound healing and the generation of new skin.